MOTS-C
Research Grade
$90
$90.00
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Certificates of Analysis
All certificates →Current batch · on shelf
98.84%
Purity by HPLC · identity confirmed by MS
15 August 2026
- Batch
- APL-MOTS5-2608-03
- Net content
- 5.07 mg
- Specification
- ≥98.0% purity · passes
Every batch is analysed in-house by HPLC and mass spectrometry and ships with a batch-specific Certificate of Analysis. Independent third-party verification is added to select batches; none is published for MOTS-C yet.
Molecular Details
Every batch is analysed in-house by HPLC & mass spectrometry and ships with a Certificate of Analysis; select batches are additionally verified by an independent third-party laboratory.
Usage & Storage
Description
Mitochondria-derived peptide activating AMPK signalling. Studied in metabolic-regulation, insulin-signalling, and mitochondrial research.
- 16 amino acid mitochondrial-derived peptide
- Studied in AMPK pathway activation research
- Investigated in metabolic-homeostasis research
- Studied in mitochondrial-biogenesis gene-expression research
- Research Grade purity >=98%
MOTS-C is a 16 amino acid mitochondrial-derived peptide encoded within the 12S rRNA gene of the mitochondrial genome. Unlike nuclear-encoded peptides, MOTS-C is expressed directly from mitochondrial DNA, positioning it as a key subject in mitochondrial-nuclear communication research. Research has investigated MOTS-C's role in AMPK pathway activation, insulin sensitivity modelling, and metabolic homeostasis. In-vitro and preclinical studies have examined its capacity to regulate glucose utilisation via the folate cycle and purine biosynthesis pathways, independent of canonical insulin signalling. Further research has explored its activity as an exercise-responsive peptide, with expression observed to increase in skeletal muscle and plasma under physical stress conditions. MOTS-C has also been studied in the context of cellular ageing, with research suggesting involvement in stress resistance and mitochondrial biogenesis regulation. Supplied as a lyophilised white powder. Supplied strictly for in-vitro laboratory research. Not for human or veterinary consumption.
Research & Guides
Frequently Asked Questions
Is MOTS-C legal to buy in Australia?
MOTS-C is supplied strictly as a research chemical for in-vitro laboratory use. It is not approved for human therapeutic use in Australia and is not for human or animal consumption. Researchers are responsible for compliance with Therapeutic Goods Administration (TGA) regulations and their institution's protocols.
What purity is MOTS-C?
We specify ≥98% purity — the High-Tier Research Grade (commercial RUO) standard. Every batch is analysed in-house by HPLC and mass spectrometry and ships with a Certificate of Analysis; select batches also undergo independent, third-party purity verification.
Does MOTS-C ship with a Certificate of Analysis (COA)?
Yes — every batch ships with a batch-specific COA documenting HPLC purity and mass-spectrometry identity. 3 MOTS-C batch certificates are published in full at australianpeptidelabs.com.au/certificates/mots-c, so the analysis can be read before ordering and the batch number printed on the vial matched against it.
Where can I buy MOTS-C in Australia?
MOTS-C can be ordered here from Australian Peptide Labs for in-vitro research use, dispatched same day from within Australia with a COA included.
Do you provide dosing or administration guidance for MOTS-C?
No. As these compounds are supplied for laboratory research only, we do not provide dosing or administration protocols. Our research library covers reconstitution and concentration calculations for in-vitro work.